Zetpil Curcumin 95 SR Plus 4 Hour Sustained Release Suppositories, 30 Count

Curcumin is the most active of the three curcuminoids found in turmeric. Curcumin may provide anti-inflammatory and cardiovascular benefits. Curcmin is a chemical of the polyphenol family derived from the rhizome Curcuma longa L. The dried, ground product of this root is the common spice known as turmeric. Turmeric consists of Curcuminoids, which include curcumin (diferuloyl methane), demethoxycurcumin, and bisdemethoxycurcmin. Curcumin has also been suggested to support the chelation of iron from the body. Curcumin inhibits the cox 2 enzyme, lipoxygenase (LOX), and inducible nitric oxide synthase (iNOS) reducing inflammation in the joints. Curcumin helps provide support for bone and joint health including arthritis. Curcumin has been indicated to support several aspects of cardiovascular health. People with high homocysteine levels have been found to have endothelial cells which do not function properly. Endothelial cells line the inside of blood vessels and prevent blood from clotting and plaques from forming. Curcumin has been indicated to prevent this dysfunction. C-Reactive Protein (CRP)is a protein which the body produces as a marker of inflammation and has been shown damage endothelial cells. This results in increased evidence vascular disease and blood clotting. Curcumin has been shown in studies to inhibit the effect of CRP on these endothelial cells.